Check to see if you are using a valid shortcut, linked to a working Garment Designer application.
You can always delete the shortcut. Go to your program folder and create a new shortcut or alias to be sure you have a working shortcut.
On Windows this can also appear when a file has been corrupted or if the user has moved/copied program files around incorrectly. You can re-install the program or run a system file check to try and repair the corrupted file.